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KMID : 0882420160900020159
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Korean Journal of Medicine
2016 Volume.90 No. 2 p.159 ~ p.162
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Chronic Myeloid Leukemia Relapsing as Isolated Extramedullary Disease Presenting as a Cardiac Mass
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변성규:Byeon Seong-Gyu
김희경:Kim Hee-Kyung/문지훈:Moon Ji-Hoon/문성미:Moon Seong-Mi/박지은:Park Jee-Eun/박실비아:Park Silvia/정철원:Jung Chul-Won
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Abstract
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Allogeneic hematopoietic stem cell transplantation is the only option for chemotherapy-refractory chronic myeloid leukemia (CML). Extramedullary relapse after transplantation is rare and usually accompanies marrow relapse. Generally, the prognosis of extramedullary relapse is poor. Here, we report a man with extramedullary relapsed CML after stem cell transplantation that presented as an isolated cardiac mass, which has shown an indolent course for more than 2 years, without evolving to medullary relapse during that period. This case implies that the CML clone might contribute to the development of quiescent extramedullary relapse with a benign course.
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KEYWORD
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Chronic myeloid leukemia, Granulocytic sarcoma, Cardiac tumor
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